The following are notable American Presbyterians:

• Dick Armey, former U.S. Representative; conservative Republican from Texas
• Lloyd Bentsen, former U.S. Senator and Representative from Texas
• John C. Breckinridge, Vice President of the United States under Buchanan
• William Jennings Bryan of the famous Scopes "Monkey Trial" in Tennessee 1925 and three times U.S. Presidential nominee for the Democratic Party
• James Buchanan, 15th U.S. President
• Frederick Buechner, author of fantasy novels and non-fiction religious books
• Aaron Burr, U.S. Vice-President under Jefferson
• The Rev. Aaron Burr, co-founder of Princeton University
• John C. Calhoun, U.S. Vice-President under Adams and Jackson
• Andrew Carnegie, richest man in the world in the late 19th century
• Jim Carrey, Canadian-born international superstar
• Grover Cleveland,
  
  
  
  22nd and 24th U.S. President
• Brian DePalma, film director; raised as a Presbyterian
• Bob Dole, 1996 Republican nominee for President
• Elizabeth Dole, senior United States senator from North Carolina
• John Foster Dulles, U.S. Secretary of State in the Eisenhower Administration
• Dwight D. Eisenhower, 34th President
• Bill Frist, current Senate Majority Leader
• Lamar Alexander, junior United States Senator from Tennessee
• Jay Rockefeller, junior United States Senator from West Virginia
• Mel Watt, Congressman from North Carolina and Chairman of the Congressional Black Caucus.
• John Glenn, Astronaut, United States Senator
• William Henry Green, Hebrew scholar
• John Marshall Harlan, Supreme Court Justice
• Katherine Harris, Florida Secretary of State during the 2000 election crisis and current congresswoman (R)
• Benjamin Harrison, 23rd U.S. President
• Rutherford B. Hayes, 19th U.S. President
• Patricia Heaton, famous portrayal of Debra Barone in Everybody Loves Raymond
• A. A. Hodge, seminary professor
• Charles Hodge, seminary professor
• Andrew Jackson,
  
  
  
  7th U.S. President
• Stonewall Jackson, General in the Confederate Army and a great presbyterian and a teacher at V.M.I.
• Jack Kemp, former AFL and NFL pro football quarterback, U.S. Representative, Cabinet Secretary (HUD) under George W. Bush, 1996 running mate to GOP Presidential candidate Robert Dole, founder of Empower America
• David Letterman, famous talk show host who earns $32 million a year. Raised a Presbyterian
• Abraham Lincoln, 16th U.S. President
• Norman Maclean, author and academic
• James Knox Polk, 11th U.S. President (converted from Presbyterianism to Methodism)
• Reverend John Rankin, American minister and abolitionist
• Condoleezza Rice, Secretary of State (2005- )
• Ronald Reagan, 40th U.S. President
• The Rev. Fred Rogers, also known as the famous Mister Rogers, was an ordained Presbyterian Minister
• William Henry Sheppard, one of the earliest African-American Presbyterian missionaries, champion of indigenous rights in the Congo Free State
• Jimmy Stewart, actor
• Norman Thomas ran for President as the Socialist Party candidate in 1928
• Daniel D. Tompkins, U.S. Vice-President under Monroe
• Mark Twain, American author (but was a Congregationalist when he lived in Hartford in his later life)
• Henry A. Wallace, U.S. Vice-President under F.D. Roosevelt
• Helen Walton, wife of late Sam Walton and heiress to the Wal-Mart fortune
• Jim Walton, heir of Wal-Mart Stores
• John Walton, heir of Wal-Mart Stores
• Sam Walton, founder of Wal-Mart Stores
• S. Robson Walton, Sam Walton's eldest son, Chairman & President of Wal-Mart Stores
• Mark Warner, Former Virgina Governor-(D)
• Derek Webb, singer-songwriter
• Benjamin Breckinridge Warfield, Princeton Seminary professor
• William A. Wheeler, U.S. Vice-President under Hayes
• Christine Todd Whitman, former governor of New Jersey
• Woodrow Wilson, 28th President
• The Rev. John Witherspoon, only clergyman to sign the Declaration of Independence