Knob Creek Church of Christ was the first Restoration Church to use the name "Church of Christ".

Some of the early Settlers arriving in Graves County, Kentucky brought with them the teachings of some of the great Restoration preachers, and wanted to have a local church where they could worship. These settlers located John Parkhill from Calloway County, Kentucky and sent one of their members to summon him to help found the congregation. In June, 1834, the congregation was established in the home of member Simon

The Church has since been through three buildings. The latest was built in 1957 and currently sits in Dukedom, Kentucky on the Kentucky/Tennessee state line. It currently has 19 members. The church jokes about sitting on the state line, and the line is literally in front of the communion table. The minister stands in Kentucky and preaches to the congregation which sits in Tennessee during the services. Many other Churches of Christ have branched from this particular church and are also still currently in existence today.